By combining the ICP source's nearly full-element high ionization efficiency with the synchronized detection of a magnetic sector multi-collector, it achieves high-precision isotope ratios comparable to TIMS while keeping flexible sample introduction. It supports laser ablation for micro-regional in situ analysis and is widely used in studies of Sr-Nd-Hf-Pb-Os and non-traditional stable isotope systems, making it a major analytical platform in isotope geochemistry, nuclear forensics, environmental tracing, and metallomics.